I guess the thing to consider while having drugs is that it might take your body into a completely different state. This state might be completely outside any normal experience. If any understanding has to be gained from this, this experience would need to be integrated into your existing knowledge based on your exploration. If this state is far far beyond what you’ve explored, its like a 5yr old child getting a glimpse of what it would feel like when its 45yrs old, just for an hour or so. How would it be able to integrate this experience once its back into its child mind?!. General an outlier experience is initially disturbing until it gets integrated with your understanding. If a lot of far away outliers are introduced in a short time, then it will put all your energies on it until you figure out how this fits into your definition of self. For example, the vipassana retreat created strong outliers which I kept working on for 6-7months. Now almost all of it is integrated and my perspective is at the next level on everything. So I have stabilized again. So in brief, a unique novel experience will trigger intense questioning and pull your energies towards understanding and integrating the experience. This journey is very interesting but heavily preoccupying, so external pressures will create problems. A lot of things are expected out of you in daily life. Fulfilling social expectations can take an entire lifetime out of you, and still you would never be completely satisfied.